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Lipo800 Forte, Carboxylic Acid

 

Lipo800 Forte is a high-stability, highly hydrophobic NIR fluorophore with peak emission ≈ 800 nm for use with Channel #2 of the FLARE® imaging system. Because of its lipophilic and cationic structure, it penetrates cell membranes rapidly and can be used to label living cells, making identification and tracking possible, both in vitro and in vivo. Depending on the cell type, and the presence of anionic transporters or efflux pumps, Lipo800 Forte can be retained for days within living cells, with cell division leading to dilution of the signal. Lipo800 Forte has a single carboxylic acid and no other reactive groups for chemical conjugation, but is also available as a convenient reactive NHS ester or maleimide derivative for one-step conjugation. Because of its chemical structure, Lipo800 Forte can facilitate the transport of other small molecules, including RNA and DNA, across cell membranes to the interior of the cell.

Specifications

  • Chemical
  • Optical
  • Documents
CHEMICAL PROPERTIES
Chemical Name Confidential
CAS Number N/A
Chemical Structure (2D/3D) Confidential
Molecular Weight 711 as a trifluoroacetate salt
Log D, pH 7.4 6.92 (JChem Calculation)
Typical purity (@210 nm/@peak absorbance) ≥ 92%
PHYSICOCHEMICAL PROPERTIES
Ligand-Match™ Compatibility N/A (see reactive derivatives for labeling options)
SOLVENT SOLUBILITY (Super-Saturation Method)
PBS, pH 7.4 Insoluble (<0.0002 mg/mL)
100% serum, pH 7.4 Insoluble (<0.033 mg/mL)
DMSO 380 mg/mL (535 mM)

Disclaimer: For laboratory research use only. Not for use in diagnostic or therapeutic applications. Not for human or veterinary use.

FLARE® CHANNEL COMPABILITY
Channel #2 (≈ 800 nm NIR fluorescence)
OPTICAL PROPERTIES PBS, PH 7.4 100% SERUM, PH 7.4 DMSO
Excitation Max (nm) 757 761 767
Emission Max (nm) 774 778 786
Stokes Shift (nm) 17 17 18
Extinction Coefficient (@ Ex max) 157,500 143,500 190,000
Quantum Yield (%) – – –

Lipo800 Forte in PBS

Lipo800 Forte in FBS

Lipo800 Forte in DMSO

Disclaimer: For laboratory research use only. Not for use in diagnostic or therapeutic applications. Not for human or veterinary use.

  • Product Brochure
  • Instructions for Use
  • Safety Data Sheet (Formerly MSDS)

Disclaimer: For laboratory research use only. Not for use in diagnostic or therapeutic applications. Not for human or veterinary use.

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  • About us
    • History of FLARE®
    • Awards & Distinctions
  • FLARE®
    • Unique Features
    • Research Imaging Systems
    • Research Contrast Agents
    • Accessories
    • Services
    • Applications
  • Sales & Distribution
    • Distributors
    • Contact Curadel Sales
    • Leasing Options
  • Resource Sharing
    • Academic Metrics
    • Presentations
    • Publications
    • Request Research Reagents
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  • Contact Us
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