Curadel ResVet Imaging commercializes ZW800-1, the world’s first zwitterionic (i.e., geometrically-balanced, electrically neutral, polyionic polymethines) near-infrared fluorophore. Available as either a carboxylic acid or, for one-step conjugation to targeting ligands, as a N-hydroxysuccimimidyl (NHS) ester, ZW800-1 exhibits extremely low non-specific background binding both in vitro and in vivo, thus improving the signal-to-background ration in virtually all biomedical imaging applications.