Lipo700 Forte, NHS Ester

Lipo700 Forte NHS is a high-stability, highly hydrophobic NIR fluorophore with peak emission ≈ 700 nm for use with Channel #1 of the FLARE^® imaging system. Lipo700 Forte-NHS can label virtually any small molecule, peptide, peptidomimetic, protein, antibody, or nanoparticle having a primary amine or other strong nucleophile, in a single-step reaction. Because of its lipophilic and cationic structure, final conjugates of Lipo700 Forte are often able to penetrate cell membranes rapidly, thus serving as a shuttle for DNA, RNA, and other small molecules.

CHEMICAL PROPERTIES
Chemical Name	Confidential
CAS Number	Confidential
Chemical Structure (2D/3D)	Confidential
Molecular Weight	742 as a trifluoroacetate salt
Log D, pH 7.4	4.52 (JChem Calculation)
Typical purity (@210 nm/@peak absorbance)	≥ 92%

PHYSICOCHEMICAL PROPERTIES
Ligand-Match™ Compatibility		N/A (see reactive derivatives for labeling options)
SOLVENT		SOLUBILITY (Super-Saturation Method)
	PBS, pH 7.4	Insoluble (<0.01 mg/mL)
	100% serum, pH 7.4	Insoluble (<0.01 mg/mL)
	DMSO	918 mg/mL (1.2 M)

Disclaimer: For laboratory research use only. Not for use in diagnostic or therapeutic applications. Not for human or veterinary use.

FLARE® CHANNEL COMPABILITY
Channel #1 (≈ 700 nm NIR fluorescence)

OPTICAL PROPERTIES	PBS, PH 7.4	100% SERUM, PH 7.4	DMSO
Excitation Max (nm)	640	649	646
Emission Max (nm)	666	671	668
Stokes Shift (nm)	26	22	22
Extinction Coefficient (@ Ex max)	138,500	131,500	139,500
Quantum Yield (%)	–	–	–

Disclaimer: For laboratory research use only. Not for use in diagnostic or therapeutic applications. Not for human or veterinary use.

Lipo700 Forte, NHS Ester

Specifications

Curadel, LLC