Lipo800 Forte, NHS Ester

Lipo800 Forte NHS is a high-stability, highly hydrophobic NIR fluorophore with peak emission ≈ 800 nm for use with Channel #2 of the FLARE^® imaging system. Lipo800 Forte-NHS can label virtually any small molecule, peptide, peptidomimetic, protein, antibody, or nanoparticle having a primary amine or other strong nucleophile, in a single-step reaction. Because of its lipophilic and cationic structure, final conjugates of Lipo800 Forte are often able to penetrate cell membranes rapidly, thus serving as a shuttle for DNA, RNA, and other small molecules.

CHEMICAL PROPERTIES
Chemical Name	Confidential
CAS Number	N/A
Chemical Structure (2D/3D)	Confidential
Molecular Weight	808 as a trifluoroacetate salt
Log D, pH 7.4	5.52 (JChem Calculation)
Typical purity (@210 nm/@peak absorbance)	≥ 92%

PHYSICOCHEMICAL PROPERTIES
Ligand-Match™ Compatibility		N/A (see reactive derivatives for labeling options)
SOLVENT		SOLUBILITY (Super-Saturation Method)
	PBS, pH 7.4	Insoluble
	100% serum, pH 7.4	Insoluble
	DMSO	162 mg/mL (200mM)

Disclaimer: For laboratory research use only. Not for use in diagnostic or therapeutic applications. Not for human or veterinary use.

FLARE® CHANNEL COMPABILITY
Channel #2 (≈ 800 nm NIR fluorescence)

OPTICAL PROPERTIES	PBS, PH 7.4	100% SERUM, PH 7.4	DMSO
Excitation Max (nm)	757	761	767
Emission Max (nm)	774	778	786
Stokes Shift (nm)	17	17	18
Extinction Coefficient (@ Ex max)	157,500	143,500	190,000
Quantum Yield (%)	–	–	–

Disclaimer: For laboratory research use only. Not for use in diagnostic or therapeutic applications. Not for human or veterinary use.

Lipo800 Forte, NHS Ester

Specifications

Curadel, LLC