ZW800-1 Forte, Maleimide

ZW800-1 Forte-Mal is a zwitterionic, general-purpose NIR fluorophore with peak emission ≈ 800 nm for use with Channel #2 of the FLARE® imaging system. Equipped with a highly reactive maleimide functionality, ZW800-1 Forte-Mal can label virtually any small molecule, peptide, peptidomimetic, protein, antibody, or nanoparticle having a free thiol in a single-step reaction using mild conditions. Because of its “zwitterionic” chemical structure, it exhibits extremely low non-specific binding and uptake in vitro and in vivo, and can help solubilize poorly soluble targeting ligands.

CHEMICAL PROPERTIES
Chemical Name	Confidential
CAS Number	N/A
Molecular Weight	1163 (TFA salt)
Log D, pH 7.4	-0.78 (JChem calculation)
Typical purity (@210 nm/@peak absorbance)	≥ 93%

PHYSICOCHEMICAL PROPERTIES
N/A
SOLUBILITY (Saturation Method)
TBD
TBD
TBD
Do not use neutral pH, salt-containing solvents, such as saline and phosphate buffers, for stock solutions because precipitation may occur over time.

FLARE® CHANNEL COMPABILITY

Channel #2 (≈ 800 nm NIR fluorescence)

OPTICAL PROPERTIES	PBS, PH 7.4	DMSO	100% SERUM, PH 7.4
Excitation Max (nm)	685 / 754	778	685 /754
Emission Max (nm)	772	792	772
Stokes Shift (nm)	12	14	18
Extinction Coefficient (@ Ex max)	168,500 / 98,500	222,500	135,000 /115,000
Quantum Yield (%)	–	–	–

Product Brochure

Instructions for Use

ZW800-1 Forte, Maleimide

Specifications

Curadel, LLC