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ZW800-1 Forte, Maleimide

 

ZW800-1 Forte-Mal is a zwitterionic, general-purpose NIR fluorophore with peak emission ≈ 800 nm for use with Channel #2 of the FLARE® imaging system. Equipped with a highly reactive maleimide functionality, ZW800-1 Forte-Mal can label virtually any small molecule, peptide, peptidomimetic, protein, antibody, or nanoparticle having a free thiol in a single-step reaction using mild conditions. Because of its “zwitterionic” chemical structure, it exhibits extremely low non-specific binding and uptake in vitro and in vivo, and can help solubilize poorly soluble targeting ligands.

Specifications

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CHEMICAL PROPERTIES
Chemical Name Confidential
CAS Number N/A
Molecular Weight 1163 (TFA salt)
Log D, pH 7.4 -0.78 (JChem calculation)
Typical purity (@210 nm/@peak absorbance)

 

≥ 93%

 

PHYSICOCHEMICAL PROPERTIES
N/A
SOLUBILITY (Saturation Method)
TBD
TBD
TBD
Do not use neutral pH, salt-containing solvents, such as saline and phosphate buffers, for stock solutions because precipitation may occur over time.
FLARE® CHANNEL COMPABILITY
Channel #2 (≈ 800 nm NIR fluorescence)

 

OPTICAL PROPERTIES PBS, PH 7.4 DMSO 100% SERUM, PH 7.4
Excitation Max (nm) 685 / 754 778 685 /754
Emission Max (nm) 772 792 772
Stokes Shift (nm) 12 14 18
Extinction Coefficient (@ Ex max) 168,500 / 98,500 222,500 135,000 /115,000
Quantum Yield (%) – – –

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  • About us
    • History of FLARE®
    • Awards & Distinctions
  • FLARE®
    • Unique Features
    • Research Imaging Systems
    • Research Contrast Agents
    • Accessories
    • Services
    • Applications
  • Sales & Distribution
    • Distributors
    • Contact Curadel Sales
    • Leasing Options
  • Resource Sharing
    • Academic Metrics
    • Presentations
    • Publications
    • Request Research Reagents
    • Research Protocols
  • Contact Us
The Curadel Companies